Drug interactions
Lycopus + Tolazamide
Severity: Minor
Lycopus and Tolazamide: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Lycopus (bugleweed) has reported hypoglycemic and thyroid-suppressing properties, so combining it with a sulfonylurea might increase the risk of low blood glucose. The evidence is theoretical.
What this interaction means in plain words
Lycopus and Tolazamide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Possible additive glucose-lowering effect; the mechanism is not well established.
What to do
Monitor blood glucose when lycopus is used with tolazamide, and counsel the patient on hypoglycemia symptoms. Reduce the tolazamide dose if glucose falls.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Tolazamide
- Disopyramide + Tolazamide Major
- Insulin degludec-liraglutide + Tolazamide Major
- Aceclofenac + Tolazamide Moderate
- Acemetacin + Tolazamide Moderate
- Acetylsalicylic acid + Tolazamide Moderate
- Albiglutide + Tolazamide Moderate
Frequently asked questions
Can I take Lycopus with Tolazamide?
MediHelp rates the interaction as minor. Lycopus and Tolazamide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Lycopus (bugleweed) has reported hypoglycemic and thyroid-suppressing properties, so combining it with a sulfonylurea might increase the risk of low blood glucose. The evidence is theoretical.
How serious is the interaction between Lycopus and Tolazamide?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood glucose when lycopus is used with tolazamide, and counsel the patient on hypoglycemia symptoms. Reduce the tolazamide dose if glucose falls.
What other medicines interact with Tolazamide?
MediHelp also lists interactions of Tolazamide with, for example, Disopyramide, Insulin degludec-liraglutide, Aceclofenac. The full list is on the Tolazamide page.
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