Drug interactions
Magnesium citrate + Streptomycin
Severity: Minor
Magnesium citrate and Streptomycin: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Aminoglycosides such as streptomycin can cause renal magnesium wasting, leading to hypomagnesemia. In addition, magnesium excess can potentiate neuromuscular blockade seen with aminoglycosides. Occasional laxative doses seldom matter clinically.
What this interaction means in plain words
Magnesium citrate and Streptomycin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Magnesium citrate belongs to Gastrointestinal Tract; Streptomycin belongs to Anti Bacterial.
Why it happens
Aminoglycoside tubular toxicity increases urinary magnesium loss.
What to do
No action is needed for occasional use. Monitor serum magnesium during prolonged aminoglycoside therapy and avoid repeated magnesium laxative doses in patients with neuromuscular risk.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Magnesium citrate
- Ciprofloxacin + Magnesium citrate Major
- Baloxavir marboxil + Magnesium citrate Moderate
- Bictegravir + Magnesium citrate Moderate
- Cabotegravir + Magnesium citrate Moderate
- Cholecalciferol + Magnesium citrate Moderate
- Deferiprone + Magnesium citrate Moderate
Other interactions of Streptomycin
Frequently asked questions
Can I take Magnesium citrate with Streptomycin?
MediHelp rates the interaction as minor. Magnesium citrate and Streptomycin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Aminoglycosides such as streptomycin can cause renal magnesium wasting, leading to hypomagnesemia. In addition, magnesium excess can potentiate neuromuscular blockade seen with aminoglycosides. Occasional laxative doses seldom matter clinically.
How serious is the interaction between Magnesium citrate and Streptomycin?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No action is needed for occasional use. Monitor serum magnesium during prolonged aminoglycoside therapy and avoid repeated magnesium laxative doses in patients with neuromuscular risk.
What other medicines interact with Magnesium citrate?
MediHelp also lists interactions of Magnesium citrate with, for example, Ciprofloxacin, Baloxavir marboxil, Bictegravir. The full list is on the Magnesium citrate page.
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