Drug interactions
Maitake + Repaglinide
Severity: Minor
Maitake and Repaglinide: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Maitake mushroom extracts have lowered blood glucose in animal studies. Combined with repaglinide, an additive glucose-lowering effect and hypoglycemia are conceivable, though human data are lacking.
What this interaction means in plain words
Maitake and Repaglinide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Possible additive hypoglycemic effect based on animal data; not established in humans.
What to do
Monitor blood glucose when maitake supplements are started or stopped. Adjust the repaglinide dose if hypoglycemia occurs.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Repaglinide
- Gemfibrozil + Repaglinide Contraindicated
- Clarithromycin + Repaglinide Major
- Clopidogrel + Repaglinide Major
- Cobicistat + Repaglinide Major
- Cyclosporine + Repaglinide Major
- Cyclosporin + Repaglinide Major
Frequently asked questions
Can I take Maitake with Repaglinide?
MediHelp rates the interaction as minor. Maitake and Repaglinide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Maitake mushroom extracts have lowered blood glucose in animal studies. Combined with repaglinide, an additive glucose-lowering effect and hypoglycemia are conceivable, though human data are lacking.
How serious is the interaction between Maitake and Repaglinide?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood glucose when maitake supplements are started or stopped. Adjust the repaglinide dose if hypoglycemia occurs.
What other medicines interact with Repaglinide?
MediHelp also lists interactions of Repaglinide with, for example, Gemfibrozil, Clarithromycin, Clopidogrel. The full list is on the Repaglinide page.
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