Drug interactions
Marijuana + Tolazamide
Severity: Minor
Marijuana and Tolazamide: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Cannabis may increase appetite and can alter glucose levels, and its effect on glycemic control is variable. Any antagonism of tolazamide is poorly characterized.
What this interaction means in plain words
Marijuana and Tolazamide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Mechanism not well established; cannabinoids may affect insulin sensitivity and food intake.
What to do
Monitor blood glucose in regular cannabis users and counsel on consistent intake.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Tolazamide
- Disopyramide + Tolazamide Major
- Insulin degludec-liraglutide + Tolazamide Major
- Aceclofenac + Tolazamide Moderate
- Acemetacin + Tolazamide Moderate
- Acetylsalicylic acid + Tolazamide Moderate
- Albiglutide + Tolazamide Moderate
Frequently asked questions
Can I take Marijuana with Tolazamide?
MediHelp rates the interaction as minor. Marijuana and Tolazamide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Cannabis may increase appetite and can alter glucose levels, and its effect on glycemic control is variable. Any antagonism of tolazamide is poorly characterized.
How serious is the interaction between Marijuana and Tolazamide?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood glucose in regular cannabis users and counsel on consistent intake.
What other medicines interact with Tolazamide?
MediHelp also lists interactions of Tolazamide with, for example, Disopyramide, Insulin degludec-liraglutide, Aceclofenac. The full list is on the Tolazamide page.
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