Drug interactions
Meclofenamate + Neomycin
Severity: Minor
Meclofenamate and Neomycin: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
NSAIDs can reduce aminoglycoside renal clearance, noted mainly in preterm infants. Oral neomycin is poorly absorbed, so relevance is small.
What this interaction means in plain words
Meclofenamate and Neomycin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
NSAID-related reduction in renal perfusion lowers aminoglycoside clearance.
What to do
No routine action; monitor renal function in neonates or patients with renal impairment.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
Pro+ members
Unlock the full page
Create an account and start a Pro+ trial to unlock the full management advice for Meclofenamate and Neomycin, the additional notes, the evidence detail and the whole-prescription interaction checker.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Try Pro+ free for 14 days on the web. No card needed.
Other interactions of Neomycin
- Amikacin + Neomycin Major
- Amphotericin b deoxycholate + Neomycin Major
- Capreomycin + Neomycin Major
- Cidofovir + Neomycin Major
- Colistin + Neomycin Major
- Ethacrynic acid + Neomycin Major
Frequently asked questions
Can I take Meclofenamate with Neomycin?
MediHelp rates the interaction as minor. Meclofenamate and Neomycin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. NSAIDs can reduce aminoglycoside renal clearance, noted mainly in preterm infants. Oral neomycin is poorly absorbed, so relevance is small.
How serious is the interaction between Meclofenamate and Neomycin?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine action; monitor renal function in neonates or patients with renal impairment.
What other medicines interact with Neomycin?
MediHelp also lists interactions of Neomycin with, for example, Amikacin, Amphotericin b deoxycholate, Capreomycin. The full list is on the Neomycin page.
Full monographs, dosing and an interaction checker in the MediHelp app
Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.
