Drug interactions
Albuterol + Mefloquine
Severity: Moderate
Albuterol and Mefloquine: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Mefloquine can prolong the QT interval and albuterol can do so too, particularly at high doses, through beta-agonist induced hypokalemia. Combined use may raise arrhythmia risk.
What this interaction means in plain words
Albuterol and Mefloquine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Additive QT prolongation, with possible beta-agonist-induced hypokalemia.
What to do
Monitor ECG and serum potassium when high or frequent albuterol doses are used. Correct hypokalemia promptly.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Mefloquine
- Arsenic trioxide + Mefloquine Contraindicated
- Dronedarone + Mefloquine Contraindicated
- Ibutilide + Mefloquine Contraindicated
- Levoketoconazole + Mefloquine Contraindicated
- Mefloquine + Nilotinib Contraindicated
- Mefloquine + Pimozide Contraindicated
Frequently asked questions
Can I take Albuterol with Mefloquine?
MediHelp rates the interaction as moderate. Albuterol and Mefloquine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Mefloquine can prolong the QT interval and albuterol can do so too, particularly at high doses, through beta-agonist induced hypokalemia. Combined use may raise arrhythmia risk.
How serious is the interaction between Albuterol and Mefloquine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor ECG and serum potassium when high or frequent albuterol doses are used. Correct hypokalemia promptly.
What other medicines interact with Mefloquine?
MediHelp also lists interactions of Mefloquine with, for example, Arsenic trioxide, Dronedarone, Ibutilide. The full list is on the Mefloquine page.
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