Drug interactions
Mesalamine + Sulfamethoxazole
Severity: Minor
Mesalamine and Sulfamethoxazole: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
The mechanism and clinical significance of any interaction are unclear. A small protein binding or renal handling effect is theoretically possible but not shown to matter.
What this interaction means in plain words
Mesalamine and Sulfamethoxazole have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Mechanism not established; possible protein binding displacement.
What to do
No routine action is needed. Monitor renal function and blood counts as usual during combined therapy.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Mesalamine
Frequently asked questions
Can I take Mesalamine with Sulfamethoxazole?
MediHelp rates the interaction as minor. Mesalamine and Sulfamethoxazole have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. The mechanism and clinical significance of any interaction are unclear. A small protein binding or renal handling effect is theoretically possible but not shown to matter.
How serious is the interaction between Mesalamine and Sulfamethoxazole?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine action is needed. Monitor renal function and blood counts as usual during combined therapy.
What other medicines interact with Mesalamine?
MediHelp also lists interactions of Mesalamine with, for example, Measles mumps rubella and varicella vaccine live, Varicella virus vaccine live, Aceclofenac. The full list is on the Mesalamine page.
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