Drug reference
mesalamine
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Drug class
Gastrointestinal Tract (Azo Compounds)
Mechanism of action
Anti-inflammatory agent; mesalamine (5-aminosalicylic acid) is the active component of sulfasalazine, but specific MOA is unknown; probably inhibits prostaglandin and leukotriene synthesis and release in colon.
Common side effects
- Flatulence
- Headache
- GI discomfort
- Abdominal pain
Contraindications
- Hypersensitivity to mesalamine or salicylates Breastfeeding Rectal suspension: Hypersensitivity to salicylates, aminosalicylates or to any ingredients in the suppository vehicle Children with chickenpox or flulike symptoms
Related conditions
Frequently asked questions
What drug class is mesalamine?
mesalamine belongs to: Gastrointestinal Tract.
How does mesalamine work?
Anti-inflammatory agent; mesalamine (5-aminosalicylic acid) is the active component of sulfasalazine, but specific MOA is unknown; probably inhibits prostaglandin and leukotriene synthesis and release in colon.
What are the common side effects of mesalamine?
Flatulence, Headache, GI discomfort, Abdominal pain
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