Drug interactions
Mesalamine + Temocillin
Severity: Minor
Mesalamine and Temocillin: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Temocillin is eliminated renally and salicylates can compete for tubular secretion. With mesalamine's low systemic salicylate exposure, a significant effect is unlikely.
What this interaction means in plain words
Mesalamine and Temocillin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Theoretical competition for renal tubular organic anion secretion, extrapolated from salicylates.
What to do
No routine adjustment is needed. Adjust temocillin dose by renal function as usual.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Mesalamine
Frequently asked questions
Can I take Mesalamine with Temocillin?
MediHelp rates the interaction as minor. Mesalamine and Temocillin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Temocillin is eliminated renally and salicylates can compete for tubular secretion. With mesalamine's low systemic salicylate exposure, a significant effect is unlikely.
How serious is the interaction between Mesalamine and Temocillin?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine adjustment is needed. Adjust temocillin dose by renal function as usual.
What other medicines interact with Mesalamine?
MediHelp also lists interactions of Mesalamine with, for example, Measles mumps rubella and varicella vaccine live, Varicella virus vaccine live, Aceclofenac. The full list is on the Mesalamine page.
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