Drug interactions
Mesalamine + Ticarcillin
Severity: Minor
Mesalamine and Ticarcillin: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Ticarcillin is cleared by renal tubular secretion, which salicylates can compete with. Mesalamine produces little systemic salicylate, so a meaningful change in ticarcillin levels is unlikely.
What this interaction means in plain words
Mesalamine and Ticarcillin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Theoretical competition for renal tubular organic anion secretion, extrapolated from salicylates.
What to do
No dose change is usually needed. Monitor renal function and adjust ticarcillin dose as usual.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Mesalamine
Frequently asked questions
Can I take Mesalamine with Ticarcillin?
MediHelp rates the interaction as minor. Mesalamine and Ticarcillin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Ticarcillin is cleared by renal tubular secretion, which salicylates can compete with. Mesalamine produces little systemic salicylate, so a meaningful change in ticarcillin levels is unlikely.
How serious is the interaction between Mesalamine and Ticarcillin?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No dose change is usually needed. Monitor renal function and adjust ticarcillin dose as usual.
What other medicines interact with Mesalamine?
MediHelp also lists interactions of Mesalamine with, for example, Measles mumps rubella and varicella vaccine live, Varicella virus vaccine live, Aceclofenac. The full list is on the Mesalamine page.
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