Drug interactions
Metaproterenol + Nebivolol
Severity: Moderate
Metaproterenol and Nebivolol: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Beta-blockers antagonize metaproterenol's bronchodilator effect and may cause bronchospasm in patients with airway disease. Nebivolol is beta-1 selective, but this declines at higher doses.
What this interaction means in plain words
Metaproterenol and Nebivolol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Pharmacodynamic antagonism at beta-2 adrenergic receptors.
What to do
Monitor respiratory status and bronchodilator response. Avoid beta-blockers in patients with asthma where possible.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Nebivolol
- Acebutolol + Nebivolol Major
- Aldesleukin + Nebivolol Major
- Amiodarone + Nebivolol Major
- Atenolol-chlorthalidone + Nebivolol Major
- Atenolol + Nebivolol Major
- Betaxolol + Nebivolol Major
Frequently asked questions
Can I take Metaproterenol with Nebivolol?
MediHelp rates the interaction as moderate. Metaproterenol and Nebivolol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Beta-blockers antagonize metaproterenol's bronchodilator effect and may cause bronchospasm in patients with airway disease. Nebivolol is beta-1 selective, but this declines at higher doses.
How serious is the interaction between Metaproterenol and Nebivolol?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor respiratory status and bronchodilator response. Avoid beta-blockers in patients with asthma where possible.
What other medicines interact with Nebivolol?
MediHelp also lists interactions of Nebivolol with, for example, Acebutolol, Aldesleukin, Amiodarone. The full list is on the Nebivolol page.
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