Drug interactions
Metaxalone + Sage
Severity: Minor
Metaxalone and Sage: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Sage may have mild sedative effects. Combined with metaxalone it could add slightly to drowsiness, but the evidence is limited.
What this interaction means in plain words
Metaxalone and Sage have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Possible additive CNS depression; the mechanism is not well established.
What to do
Advise the patient to watch for increased drowsiness and avoid driving if affected.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Metaxalone
Frequently asked questions
Can I take Metaxalone with Sage?
MediHelp rates the interaction as minor. Metaxalone and Sage have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Sage may have mild sedative effects. Combined with metaxalone it could add slightly to drowsiness, but the evidence is limited.
How serious is the interaction between Metaxalone and Sage?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Advise the patient to watch for increased drowsiness and avoid driving if affected.
What other medicines interact with Metaxalone?
MediHelp also lists interactions of Metaxalone with, for example, Alfentanil, Belladonna and opium, Benzhydrocodone / acetaminophen. The full list is on the Metaxalone page.
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