Drug interactions
Metformin-repaglinide + Oxcarbazepine
Severity: Minor
Metformin-repaglinide and Oxcarbazepine: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Oxcarbazepine is a weak CYP3A4 inducer and could modestly reduce repaglinide exposure and glucose-lowering effect. The clinical impact is likely small.
What this interaction means in plain words
Metformin-repaglinide and Oxcarbazepine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Metformin-repaglinide belongs to Endocrine; Oxcarbazepine belongs to Central Nervous System.
Why it happens
Weak induction of CYP3A4 increases repaglinide metabolism.
What to do
Monitor blood glucose after starting or stopping oxcarbazepine and adjust the repaglinide dose if control changes.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Metformin-repaglinide
Other interactions of Oxcarbazepine
- Cabotegravir + Oxcarbazepine Contraindicated
- Oxcarbazepine + Rilpivirine Contraindicated
- Artemether / lumefantrine + Oxcarbazepine Major
- Atazanavir + Oxcarbazepine Major
- Benzhydrocodone / acetaminophen + Oxcarbazepine Major
- Bictegravir + Oxcarbazepine Major
Frequently asked questions
Can I take Metformin-repaglinide with Oxcarbazepine?
MediHelp rates the interaction as minor. Metformin-repaglinide and Oxcarbazepine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Oxcarbazepine is a weak CYP3A4 inducer and could modestly reduce repaglinide exposure and glucose-lowering effect. The clinical impact is likely small.
How serious is the interaction between Metformin-repaglinide and Oxcarbazepine?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood glucose after starting or stopping oxcarbazepine and adjust the repaglinide dose if control changes.
What other medicines interact with Metformin-repaglinide?
MediHelp also lists interactions of Metformin-repaglinide with, for example, Gemfibrozil, Apalutamide, Clarithromycin. The full list is on the Metformin-repaglinide page.
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