Drug interactions
Metformin-repaglinide + Rasagiline
Severity: Minor
Metformin-repaglinide and Rasagiline: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
There is no well-established clinically relevant interaction between rasagiline and metformin or repaglinide. MAO inhibitors have been associated with hypoglycemia in some contexts, but evidence for rasagiline is minimal.
What this interaction means in plain words
Metformin-repaglinide and Rasagiline have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Metformin-repaglinide belongs to Endocrine; Rasagiline belongs to Central Nervous System.
Why it happens
No established mechanism; a weak additive glucose-lowering effect is theoretical.
What to do
No routine adjustment is needed; check blood glucose if unexplained hypoglycemia occurs after starting rasagiline.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Metformin-repaglinide
Other interactions of Rasagiline
- Atomoxetine + Rasagiline Contraindicated
- Brimonidine + Rasagiline Contraindicated
- Bupropion-naltrexone + Rasagiline Contraindicated
- Bupropion + Rasagiline Contraindicated
- Clomipramine + Rasagiline Contraindicated
- Desvenlafaxine + Rasagiline Contraindicated
Frequently asked questions
Can I take Metformin-repaglinide with Rasagiline?
MediHelp rates the interaction as minor. Metformin-repaglinide and Rasagiline have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. There is no well-established clinically relevant interaction between rasagiline and metformin or repaglinide. MAO inhibitors have been associated with hypoglycemia in some contexts, but evidence for rasagiline is minimal.
How serious is the interaction between Metformin-repaglinide and Rasagiline?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine adjustment is needed; check blood glucose if unexplained hypoglycemia occurs after starting rasagiline.
What other medicines interact with Metformin-repaglinide?
MediHelp also lists interactions of Metformin-repaglinide with, for example, Gemfibrozil, Apalutamide, Clarithromycin. The full list is on the Metformin-repaglinide page.
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