Drug interactions
Methimazole + Ropeginterferon alfa 2b
Severity: Moderate
Methimazole and Ropeginterferon alfa 2b: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Methimazole can rarely cause agranulocytosis and other cytopenias, and interferons also suppress bone marrow. Together they may cause additive myelosuppression and infection risk.
What this interaction means in plain words
Methimazole and Ropeginterferon alfa 2b can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Additive myelosuppression.
What to do
Monitor complete blood counts with differential regularly and instruct the patient to report fever or sore throat immediately; interrupt a drug if significant cytopenia occurs.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Methimazole
- Carbamazepine + Methimazole Major
- Clozapine + Methimazole Major
- Methimazole + Propylthiouracil Major
- Methimazole + Sodium iodide i-131 Major
- Iodinated glycerol + Methimazole Moderate
- Iodine + Methimazole Moderate
Frequently asked questions
Can I take Methimazole with Ropeginterferon alfa 2b?
MediHelp rates the interaction as moderate. Methimazole and Ropeginterferon alfa 2b can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Methimazole can rarely cause agranulocytosis and other cytopenias, and interferons also suppress bone marrow. Together they may cause additive myelosuppression and infection risk.
How serious is the interaction between Methimazole and Ropeginterferon alfa 2b?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor complete blood counts with differential regularly and instruct the patient to report fever or sore throat immediately; interrupt a drug if significant cytopenia occurs.
What other medicines interact with Methimazole?
MediHelp also lists interactions of Methimazole with, for example, Carbamazepine, Clozapine, Propylthiouracil. The full list is on the Methimazole page.
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