Drug reference

methimazole

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Drug class

Endocrine (Thyroid Drugs)

Mechanism of action

Inhibits synthesis of thyroid hormone by blocking oxidation of iodine in thyroid gland; blocks synthesis of thyroxine (T4) and triiodothyronine (T3)

Common side effects

  • Hepatotoxicity
  • Alopecia
  • Pruritus
  • Rash
  • Agranulocytosis
  • Aplastic anemia
  • Neuritis

Related conditions

Frequently asked questions

What drug class is methimazole?

methimazole belongs to: Endocrine.

How does methimazole work?

Inhibits synthesis of thyroid hormone by blocking oxidation of iodine in thyroid gland; blocks synthesis of thyroxine (T4) and triiodothyronine (T3)

What are the common side effects of methimazole?

Hepatotoxicity, Alopecia, Pruritus, Rash, Agranulocytosis, Aplastic anemia, Neuritis

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