Drug interactions
Methocarbamol + Triclofos
Severity: Moderate
Methocarbamol and Triclofos: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Triclofos is a sedative-hypnotic whose active metabolite is trichloroethanol, and methocarbamol adds further central depression. The combination can cause excessive sedation and impaired psychomotor performance.
What this interaction means in plain words
Methocarbamol and Triclofos can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Additive CNS depressant effects.
What to do
Start with reduced doses of the sedative and monitor for oversedation. Advise patients against driving or operating machinery.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Pro+ members
Unlock the full page
Create an account and start a Pro+ trial to unlock the full management advice for Methocarbamol and Triclofos, the additional notes, the evidence detail and the whole-prescription interaction checker.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Try Pro+ free for 7 days on the web. No card needed.
Other interactions of Methocarbamol
Frequently asked questions
Can I take Methocarbamol with Triclofos?
MediHelp rates the interaction as moderate. Methocarbamol and Triclofos can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Triclofos is a sedative-hypnotic whose active metabolite is trichloroethanol, and methocarbamol adds further central depression. The combination can cause excessive sedation and impaired psychomotor performance.
How serious is the interaction between Methocarbamol and Triclofos?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Start with reduced doses of the sedative and monitor for oversedation. Advise patients against driving or operating machinery.
What other medicines interact with Methocarbamol?
MediHelp also lists interactions of Methocarbamol with, for example, Alfentanil, Amobarbital, Belladonna and opium. The full list is on the Methocarbamol page.
Full monographs, dosing and an interaction checker in the MediHelp app
Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.
