Drug interactions
Methoxsalen + Telmisartan-amlodipine
Severity: Moderate
Methoxsalen and Telmisartan-amlodipine: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Hydrochlorothiazide, if present in the product, is photosensitizing and may add to the phototoxic effect of methoxsalen with UVA exposure, raising the risk of burns or skin reactions. Telmisartan and amlodipine themselves have little relevance to this interaction.
What this interaction means in plain words
Methoxsalen and Telmisartan-amlodipine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Methoxsalen belongs to Anti Fungals; Telmisartan-amlodipine belongs to Cardiovascular.
Why it happens
Additive photosensitizing effects of methoxsalen and thiazide diuretics.
What to do
Counsel on strict sun protection and review the UVA dosing schedule, and consider an alternative to a thiazide-containing antihypertensive during phototherapy.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Pro+ members
Unlock the full page
Create an account and start a Pro+ trial to unlock the full management advice for Methoxsalen and Telmisartan-amlodipine, the additional notes, the evidence detail and the whole-prescription interaction checker.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Try Pro+ free for 7 days on the web. No card needed.
Other interactions of Telmisartan-amlodipine
- Aliskiren + Telmisartan-amlodipine Contraindicated
- Sparsentan + Telmisartan-amlodipine Contraindicated
- Amifostine + Telmisartan-amlodipine Major
- Amiloride + Telmisartan-amlodipine Major
- Benazepril + Telmisartan-amlodipine Major
- Candesartan + Telmisartan-amlodipine Major
Other interactions of Methoxsalen
- Fezolinetant + Methoxsalen Contraindicated
- Demeclocycline + Methoxsalen Major
- Fedratinib + Methoxsalen Major
- Methoxsalen + Pirfenidone Major
- Methoxsalen + Tasimelteon Major
- Adapalene + Methoxsalen Moderate
Frequently asked questions
Can I take Methoxsalen with Telmisartan-amlodipine?
MediHelp rates the interaction as moderate. Methoxsalen and Telmisartan-amlodipine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Hydrochlorothiazide, if present in the product, is photosensitizing and may add to the phototoxic effect of methoxsalen with UVA exposure, raising the risk of burns or skin reactions. Telmisartan and amlodipine themselves have little relevance to this interaction.
How serious is the interaction between Methoxsalen and Telmisartan-amlodipine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Counsel on strict sun protection and review the UVA dosing schedule, and consider an alternative to a thiazide-containing antihypertensive during phototherapy.
What other medicines interact with Telmisartan-amlodipine?
MediHelp also lists interactions of Telmisartan-amlodipine with, for example, Aliskiren, Sparsentan, Amifostine. The full list is on the Telmisartan-amlodipine page.
Full monographs, dosing and an interaction checker in the MediHelp app
Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.
