Drug interactions
Methyl aminolevulinate + Sulindac
Severity: Minor
Methyl aminolevulinate and Sulindac: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Methyl aminolevulinate is used with light in photodynamic therapy and drugs that cause photosensitivity may amplify skin reactions. Sulindac has occasionally been associated with photosensitivity. Systemic exposure from topical methyl aminolevulinate is low, so the interaction is mostly theoretical.
What this interaction means in plain words
Methyl aminolevulinate and Sulindac have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Possible additive photosensitization in treated skin.
What to do
Review other photosensitizing drugs before photodynamic therapy and monitor the treated area for exaggerated erythema or pain. Continued NSAID use is generally acceptable if needed.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Sulindac
- Ketorolac intranasal + Sulindac Contraindicated
- Ketorolac + Sulindac Contraindicated
- Aceclofenac + Sulindac Major
- Acetylsalicylic acid + Sulindac Major
- Alteplase + Sulindac Major
- Amiloride + Sulindac Major
Frequently asked questions
Can I take Methyl aminolevulinate with Sulindac?
MediHelp rates the interaction as minor. Methyl aminolevulinate and Sulindac have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Methyl aminolevulinate is used with light in photodynamic therapy and drugs that cause photosensitivity may amplify skin reactions. Sulindac has occasionally been associated with photosensitivity. Systemic exposure from topical methyl aminolevulinate is low, so the interaction is mostly theoretical.
How serious is the interaction between Methyl aminolevulinate and Sulindac?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Review other photosensitizing drugs before photodynamic therapy and monitor the treated area for exaggerated erythema or pain. Continued NSAID use is generally acceptable if needed.
What other medicines interact with Sulindac?
MediHelp also lists interactions of Sulindac with, for example, Ketorolac intranasal, Ketorolac, Aceclofenac. The full list is on the Sulindac page.
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