Drug interactions
Metipranolol + Nebivolol
Severity: Moderate
Metipranolol and Nebivolol: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Metipranolol eye drops are a nonselective beta blocker that can be absorbed systemically. With oral nebivolol, additive bradycardia, hypotension and bronchospasm may occur.
What this interaction means in plain words
Metipranolol and Nebivolol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Additive beta-adrenergic blockade from systemically absorbed ophthalmic drug.
What to do
Monitor pulse and blood pressure, and ask about wheeze or dizziness. Consider a non-beta-blocker glaucoma treatment if systemic effects develop.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Nebivolol
- Acebutolol + Nebivolol Major
- Aldesleukin + Nebivolol Major
- Amiodarone + Nebivolol Major
- Atenolol-chlorthalidone + Nebivolol Major
- Atenolol + Nebivolol Major
- Betaxolol + Nebivolol Major
Frequently asked questions
Can I take Metipranolol with Nebivolol?
MediHelp rates the interaction as moderate. Metipranolol and Nebivolol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Metipranolol eye drops are a nonselective beta blocker that can be absorbed systemically. With oral nebivolol, additive bradycardia, hypotension and bronchospasm may occur.
How serious is the interaction between Metipranolol and Nebivolol?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor pulse and blood pressure, and ask about wheeze or dizziness. Consider a non-beta-blocker glaucoma treatment if systemic effects develop.
What other medicines interact with Nebivolol?
MediHelp also lists interactions of Nebivolol with, for example, Acebutolol, Aldesleukin, Amiodarone. The full list is on the Nebivolol page.
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