Drug interactions
Microbiota + Neomycin
Severity: Moderate
Microbiota and Neomycin: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Oral neomycin acts on gut bacteria and can reduce the engraftment of orally administered microbiota spores. This may diminish the product's therapeutic benefit.
What this interaction means in plain words
Microbiota and Neomycin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Antibacterial activity in the gut against the administered microbiota reduces engraftment.
What to do
Complete antibiotic therapy before starting the microbiota product, allowing the interval stated in the product labeling.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Neomycin
- Amikacin + Neomycin Major
- Amphotericin b deoxycholate + Neomycin Major
- Capreomycin + Neomycin Major
- Cidofovir + Neomycin Major
- Colistin + Neomycin Major
- Ethacrynic acid + Neomycin Major
Frequently asked questions
Can I take Microbiota with Neomycin?
MediHelp rates the interaction as moderate. Microbiota and Neomycin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Oral neomycin acts on gut bacteria and can reduce the engraftment of orally administered microbiota spores. This may diminish the product's therapeutic benefit.
How serious is the interaction between Microbiota and Neomycin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Complete antibiotic therapy before starting the microbiota product, allowing the interval stated in the product labeling.
What other medicines interact with Neomycin?
MediHelp also lists interactions of Neomycin with, for example, Amikacin, Amphotericin b deoxycholate, Capreomycin. The full list is on the Neomycin page.
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