Drug interactions
Minoxidil + Triamterene
Severity: Moderate
Minoxidil and Triamterene: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Both agents lower blood pressure, so combined use can cause additive hypotension. Minoxidil is usually given with a diuretic to counter fluid retention, making this combination common and generally manageable.
What this interaction means in plain words
Minoxidil and Triamterene can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Minoxidil belongs to Cardiovascular; Triamterene belongs to Cardiovascular.
Why it happens
Additive pharmacodynamic blood pressure lowering from vasodilation and diuresis.
What to do
Monitor blood pressure, volume status and electrolytes, and titrate doses gradually.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Pro+ members
Unlock the full page
Create an account and start a Pro+ trial to unlock the full management advice for Minoxidil and Triamterene, the additional notes, the evidence detail and the whole-prescription interaction checker.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Try Pro+ free for 7 days on the web. No card needed.
Other interactions of Triamterene
- Amiloride + Triamterene Contraindicated
- Eplerenone + Triamterene Contraindicated
- Potassium citrate / citric acid + Triamterene Contraindicated
- Potassium citrate + Triamterene Contraindicated
- Spironolactone + Triamterene Contraindicated
- Aceclofenac + Triamterene Major
Other interactions of Minoxidil
Frequently asked questions
Can I take Minoxidil with Triamterene?
MediHelp rates the interaction as moderate. Minoxidil and Triamterene can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Both agents lower blood pressure, so combined use can cause additive hypotension. Minoxidil is usually given with a diuretic to counter fluid retention, making this combination common and generally manageable.
How serious is the interaction between Minoxidil and Triamterene?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure, volume status and electrolytes, and titrate doses gradually.
What other medicines interact with Triamterene?
MediHelp also lists interactions of Triamterene with, for example, Amiloride, Eplerenone, Potassium citrate / citric acid. The full list is on the Triamterene page.
Full monographs, dosing and an interaction checker in the MediHelp app
Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.
