Drug interactions
Motherwort + Oxymorphone
Severity: Minor
Motherwort and Oxymorphone: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Motherwort is traditionally used as a mild sedative herb and may add to opioid drowsiness. Clinical data are scarce, so the effect is largely theoretical.
What this interaction means in plain words
Motherwort and Oxymorphone have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Possible additive sedation; the exact mechanism is not established.
What to do
Ask patients about herbal use and advise caution with driving if drowsiness occurs. Stop the herb if excessive sedation develops.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Oxymorphone
- Alvimopan + Oxymorphone Contraindicated
- Ethanol + Oxymorphone Contraindicated
- Isocarboxazid + Oxymorphone Contraindicated
- Olanzapine / samidorphan + Oxymorphone Contraindicated
- Oxymorphone + Phenelzine Contraindicated
- Oxymorphone + Selegiline transdermal Contraindicated
Frequently asked questions
Can I take Motherwort with Oxymorphone?
MediHelp rates the interaction as minor. Motherwort and Oxymorphone have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Motherwort is traditionally used as a mild sedative herb and may add to opioid drowsiness. Clinical data are scarce, so the effect is largely theoretical.
How serious is the interaction between Motherwort and Oxymorphone?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Ask patients about herbal use and advise caution with driving if drowsiness occurs. Stop the herb if excessive sedation develops.
What other medicines interact with Oxymorphone?
MediHelp also lists interactions of Oxymorphone with, for example, Alvimopan, Ethanol, Isocarboxazid. The full list is on the Oxymorphone page.
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