Drug interactions
Motherwort + Quetiapine
Severity: Minor
Motherwort and Quetiapine: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Motherwort is an herbal product traditionally used for its mild sedative effects. Taken with quetiapine, it may add to drowsiness and psychomotor impairment. Clinical data are very limited and the effect is largely predicted.
What this interaction means in plain words
Motherwort and Quetiapine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Additive CNS depressant effects; the herb's sedative activity is not well characterised.
What to do
Advise patients to report increased drowsiness and to avoid driving until the response is known. Consider stopping the herbal product if excessive sedation occurs.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Quetiapine
- Adagrasib + Quetiapine Major
- Amiodarone + Quetiapine Major
- Amisulpride + Quetiapine Major
- Amoxapine + Quetiapine Major
- Anagrelide + Quetiapine Major
- Apalutamide + Quetiapine Major
Frequently asked questions
Can I take Motherwort with Quetiapine?
MediHelp rates the interaction as minor. Motherwort and Quetiapine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Motherwort is an herbal product traditionally used for its mild sedative effects. Taken with quetiapine, it may add to drowsiness and psychomotor impairment. Clinical data are very limited and the effect is largely predicted.
How serious is the interaction between Motherwort and Quetiapine?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Advise patients to report increased drowsiness and to avoid driving until the response is known. Consider stopping the herbal product if excessive sedation occurs.
What other medicines interact with Quetiapine?
MediHelp also lists interactions of Quetiapine with, for example, Adagrasib, Amiodarone, Amisulpride. The full list is on the Quetiapine page.
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