Drug interactions
Moxisylyte + Nicardipine
Severity: Moderate
Moxisylyte and Nicardipine: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Moxisylyte is an alpha-1 blocking vasodilator, and nicardipine is a vasodilating calcium channel blocker. Combining them can cause additive hypotension, dizziness and reflex tachycardia.
What this interaction means in plain words
Moxisylyte and Nicardipine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Additive vasodilation through alpha-adrenergic blockade and calcium channel blockade.
What to do
Monitor blood pressure, including standing values, and lower the dose of one drug if symptomatic hypotension occurs.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Nicardipine
Frequently asked questions
Can I take Moxisylyte with Nicardipine?
MediHelp rates the interaction as moderate. Moxisylyte and Nicardipine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Moxisylyte is an alpha-1 blocking vasodilator, and nicardipine is a vasodilating calcium channel blocker. Combining them can cause additive hypotension, dizziness and reflex tachycardia.
How serious is the interaction between Moxisylyte and Nicardipine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure, including standing values, and lower the dose of one drug if symptomatic hypotension occurs.
What other medicines interact with Nicardipine?
MediHelp also lists interactions of Nicardipine with, for example, Amifostine, Amlodipine-olmesartan-hydrochlorothiazide, Betrixaban. The full list is on the Nicardipine page.
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