Drug interactions
Nadolol + Sodium citrate / citric acid
Severity: Minor
Nadolol and Sodium citrate / citric acid: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Alkalinizing agents may reduce the absorption of oral beta-blockers by altering gastric pH, which may slightly lower nadolol exposure. The effect is likely small.
What this interaction means in plain words
Nadolol and Sodium citrate / citric acid have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Altered gastric pH may reduce gastrointestinal absorption of oral nadolol; the mechanism is not firmly established.
What to do
Separate oral doses by about 2 hours. Monitor blood pressure and heart rate if the preparations are used regularly.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Nadolol
- Acebutolol + Nadolol Major
- Adrenaline-articaine + Nadolol Major
- Albuterol + Nadolol Major
- Amifostine + Nadolol Major
- Amiodarone + Nadolol Major
- Arformoterol + Nadolol Major
Frequently asked questions
Can I take Nadolol with Sodium citrate / citric acid?
MediHelp rates the interaction as minor. Nadolol and Sodium citrate / citric acid have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Alkalinizing agents may reduce the absorption of oral beta-blockers by altering gastric pH, which may slightly lower nadolol exposure. The effect is likely small.
How serious is the interaction between Nadolol and Sodium citrate / citric acid?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Separate oral doses by about 2 hours. Monitor blood pressure and heart rate if the preparations are used regularly.
What other medicines interact with Nadolol?
MediHelp also lists interactions of Nadolol with, for example, Acebutolol, Adrenaline-articaine, Albuterol. The full list is on the Nadolol page.
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