Drug interactions
Nadolol + Telmisartan
Severity: Moderate
Nadolol and Telmisartan: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Both drugs lower blood pressure, and the combination is commonly used but can cause excessive hypotension or bradycardia. Beta-blockers can also modestly raise potassium and impair its cellular uptake, adding to the ARB's effect, and telmisartan carries fetal toxicity risk in pregnancy regardless of this combination.
What this interaction means in plain words
Nadolol and Telmisartan can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Nadolol belongs to Cardiovascular; Telmisartan belongs to Cardiovascular.
Why it happens
Additive antihypertensive effects through beta-adrenergic blockade and angiotensin receptor blockade, with minor additive effects on potassium handling.
What to do
Monitor blood pressure, heart rate and serum potassium, particularly at initiation and with renal impairment. Adjust doses if symptomatic hypotension or hyperkalemia occurs.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Telmisartan
- Aliskiren + Telmisartan Contraindicated
- Sparsentan + Telmisartan Contraindicated
- Amifostine + Telmisartan Major
- Amiloride + Telmisartan Major
- Amlodipine-benazepril + Telmisartan Major
- Amlodipine-hydrochlorothiazide-valsartan + Telmisartan Major
Other interactions of Nadolol
- Acebutolol + Nadolol Major
- Adrenaline-articaine + Nadolol Major
- Albuterol + Nadolol Major
- Amifostine + Nadolol Major
- Amiodarone + Nadolol Major
- Arformoterol + Nadolol Major
Frequently asked questions
Can I take Nadolol with Telmisartan?
MediHelp rates the interaction as moderate. Nadolol and Telmisartan can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Both drugs lower blood pressure, and the combination is commonly used but can cause excessive hypotension or bradycardia. Beta-blockers can also modestly raise potassium and impair its cellular uptake, adding to the ARB's effect, and telmisartan carries fetal toxicity risk in pregnancy regardless of this combination.
How serious is the interaction between Nadolol and Telmisartan?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure, heart rate and serum potassium, particularly at initiation and with renal impairment. Adjust doses if symptomatic hypotension or hyperkalemia occurs.
What other medicines interact with Telmisartan?
MediHelp also lists interactions of Telmisartan with, for example, Aliskiren, Sparsentan, Amifostine. The full list is on the Telmisartan page.
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