Drug interactions
Nebivolol + Olmesartan
Severity: Moderate
Nebivolol and Olmesartan: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
The combination produces additive blood pressure reduction and may cause hypotension at initiation. Olmesartan can increase serum potassium and must be avoided in pregnancy.
What this interaction means in plain words
Nebivolol and Olmesartan can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Nebivolol belongs to Cardiovascular; Olmesartan belongs to Cardiovascular.
Why it happens
Additive antihypertensive effects; angiotensin receptor blockade reduces aldosterone-mediated potassium excretion.
What to do
Monitor blood pressure, potassium and renal function after starting or adjusting doses. Adjust therapy if hypotension or hyperkalemia occurs.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Nebivolol
- Acebutolol + Nebivolol Major
- Aldesleukin + Nebivolol Major
- Amiodarone + Nebivolol Major
- Atenolol-chlorthalidone + Nebivolol Major
- Atenolol + Nebivolol Major
- Betaxolol + Nebivolol Major
Other interactions of Olmesartan
- Aliskiren + Olmesartan Contraindicated
- Olmesartan + Sparsentan Contraindicated
- Aldesleukin + Olmesartan Major
- Amifostine + Olmesartan Major
- Amiloride + Olmesartan Major
- Amlodipine-benazepril + Olmesartan Major
Frequently asked questions
Can I take Nebivolol with Olmesartan?
MediHelp rates the interaction as moderate. Nebivolol and Olmesartan can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. The combination produces additive blood pressure reduction and may cause hypotension at initiation. Olmesartan can increase serum potassium and must be avoided in pregnancy.
How serious is the interaction between Nebivolol and Olmesartan?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure, potassium and renal function after starting or adjusting doses. Adjust therapy if hypotension or hyperkalemia occurs.
What other medicines interact with Nebivolol?
MediHelp also lists interactions of Nebivolol with, for example, Acebutolol, Aldesleukin, Amiodarone. The full list is on the Nebivolol page.
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