Drug interactions
Nebivolol + Sodium citrate / citric acid
Severity: Minor
Nebivolol and Sodium citrate / citric acid: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Oral citrate-based alkalinizing agents neutralize gastric acid and might slightly reduce nebivolol absorption. The clinical effect is probably small.
What this interaction means in plain words
Nebivolol and Sodium citrate / citric acid have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Gastric pH elevation possibly reducing nebivolol absorption.
What to do
Separate administration by about 2 hours. Monitor blood pressure if use is frequent.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Nebivolol
- Acebutolol + Nebivolol Major
- Aldesleukin + Nebivolol Major
- Amiodarone + Nebivolol Major
- Atenolol-chlorthalidone + Nebivolol Major
- Atenolol + Nebivolol Major
- Betaxolol + Nebivolol Major
Frequently asked questions
Can I take Nebivolol with Sodium citrate / citric acid?
MediHelp rates the interaction as minor. Nebivolol and Sodium citrate / citric acid have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Oral citrate-based alkalinizing agents neutralize gastric acid and might slightly reduce nebivolol absorption. The clinical effect is probably small.
How serious is the interaction between Nebivolol and Sodium citrate / citric acid?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Separate administration by about 2 hours. Monitor blood pressure if use is frequent.
What other medicines interact with Nebivolol?
MediHelp also lists interactions of Nebivolol with, for example, Acebutolol, Aldesleukin, Amiodarone. The full list is on the Nebivolol page.
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