Drug interactions
Nebivolol + Telmisartan
Severity: Moderate
Nebivolol and Telmisartan: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Both drugs lower blood pressure and are often combined deliberately, but the effect is additive and can cause excess hypotension or dizziness, especially at treatment start. Telmisartan can raise potassium, and nebivolol has little effect on it. Telmisartan is also fetotoxic in pregnancy.
What this interaction means in plain words
Nebivolol and Telmisartan can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Nebivolol belongs to Cardiovascular; Telmisartan belongs to Cardiovascular.
Why it happens
Additive antihypertensive effect from beta-1 blockade and angiotensin II receptor blockade.
What to do
Monitor blood pressure and heart rate when starting or titrating, and check potassium and renal function periodically. Avoid telmisartan in pregnancy.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Nebivolol
- Acebutolol + Nebivolol Major
- Aldesleukin + Nebivolol Major
- Amiodarone + Nebivolol Major
- Atenolol-chlorthalidone + Nebivolol Major
- Atenolol + Nebivolol Major
- Betaxolol + Nebivolol Major
Other interactions of Telmisartan
- Aliskiren + Telmisartan Contraindicated
- Sparsentan + Telmisartan Contraindicated
- Amifostine + Telmisartan Major
- Amiloride + Telmisartan Major
- Amlodipine-benazepril + Telmisartan Major
- Amlodipine-hydrochlorothiazide-valsartan + Telmisartan Major
Frequently asked questions
Can I take Nebivolol with Telmisartan?
MediHelp rates the interaction as moderate. Nebivolol and Telmisartan can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Both drugs lower blood pressure and are often combined deliberately, but the effect is additive and can cause excess hypotension or dizziness, especially at treatment start. Telmisartan can raise potassium, and nebivolol has little effect on it. Telmisartan is also fetotoxic in pregnancy.
How serious is the interaction between Nebivolol and Telmisartan?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure and heart rate when starting or titrating, and check potassium and renal function periodically. Avoid telmisartan in pregnancy.
What other medicines interact with Nebivolol?
MediHelp also lists interactions of Nebivolol with, for example, Acebutolol, Aldesleukin, Amiodarone. The full list is on the Nebivolol page.
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