Drug interactions
Neomycin + Pyridoxine
Severity: Minor
Neomycin and Pyridoxine: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Oral neomycin suppresses gut bacteria, some of which contribute to B vitamin supply. The effect on pyridoxine status is theoretical and unlikely to matter clinically.
What this interaction means in plain words
Neomycin and Pyridoxine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Reduced intestinal flora may lower microbial vitamin production.
What to do
No action needed for short courses; consider vitamin status only in prolonged use.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Neomycin
- Amikacin + Neomycin Major
- Amphotericin b deoxycholate + Neomycin Major
- Capreomycin + Neomycin Major
- Cidofovir + Neomycin Major
- Colistin + Neomycin Major
- Ethacrynic acid + Neomycin Major
Frequently asked questions
Can I take Neomycin with Pyridoxine?
MediHelp rates the interaction as minor. Neomycin and Pyridoxine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Oral neomycin suppresses gut bacteria, some of which contribute to B vitamin supply. The effect on pyridoxine status is theoretical and unlikely to matter clinically.
How serious is the interaction between Neomycin and Pyridoxine?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No action needed for short courses; consider vitamin status only in prolonged use.
What other medicines interact with Neomycin?
MediHelp also lists interactions of Neomycin with, for example, Amikacin, Amphotericin b deoxycholate, Capreomycin. The full list is on the Neomycin page.
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