Drug interactions
Nettle + Repaglinide
Severity: Minor
Nettle and Repaglinide: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Stinging nettle has shown glucose-lowering activity in animal and limited human studies. Taken with repaglinide it could potentiate the hypoglycemic effect, but the evidence is weak.
What this interaction means in plain words
Nettle and Repaglinide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Possible additive hypoglycemic effect; the mechanism is not clearly established.
What to do
Monitor blood glucose if nettle products are used regularly. Adjust the repaglinide dose if hypoglycemia occurs.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Repaglinide
- Gemfibrozil + Repaglinide Contraindicated
- Clarithromycin + Repaglinide Major
- Clopidogrel + Repaglinide Major
- Cobicistat + Repaglinide Major
- Cyclosporine + Repaglinide Major
- Cyclosporin + Repaglinide Major
Frequently asked questions
Can I take Nettle with Repaglinide?
MediHelp rates the interaction as minor. Nettle and Repaglinide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Stinging nettle has shown glucose-lowering activity in animal and limited human studies. Taken with repaglinide it could potentiate the hypoglycemic effect, but the evidence is weak.
How serious is the interaction between Nettle and Repaglinide?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood glucose if nettle products are used regularly. Adjust the repaglinide dose if hypoglycemia occurs.
What other medicines interact with Repaglinide?
MediHelp also lists interactions of Repaglinide with, for example, Gemfibrozil, Clarithromycin, Clopidogrel. The full list is on the Repaglinide page.
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