Drug interactions
Nortriptyline + Telavancin
Severity: Moderate
Nortriptyline and Telavancin: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Nortriptyline can prolong the QTc interval and slow intracardiac conduction. With telavancin, the risk of ventricular arrhythmia may increase, especially in patients with heart disease.
What this interaction means in plain words
Nortriptyline and Telavancin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Nortriptyline belongs to Central Nervous System; Telavancin belongs to Anti Bacterial.
Why it happens
Additive effects on cardiac repolarization and conduction.
What to do
Check a baseline ECG and monitor QTc and electrolytes during co-therapy. Consider an alternative antibiotic in patients with other QT risk factors.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Telavancin
- Telavancin + Thioridazine Contraindicated
- Adagrasib + Telavancin Major
- Amiodarone + Telavancin Major
- Amisulpride + Telavancin Major
- Anagrelide + Telavancin Major
- Arsenic trioxide + Telavancin Major
Other interactions of Nortriptyline
- Disopyramide + Nortriptyline Contraindicated
- Dofetilide + Nortriptyline Contraindicated
- Dronedarone + Nortriptyline Contraindicated
- Ibutilide + Nortriptyline Contraindicated
- Isocarboxazid + Nortriptyline Contraindicated
- Methylene blue + Nortriptyline Contraindicated
Frequently asked questions
Can I take Nortriptyline with Telavancin?
MediHelp rates the interaction as moderate. Nortriptyline and Telavancin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Nortriptyline can prolong the QTc interval and slow intracardiac conduction. With telavancin, the risk of ventricular arrhythmia may increase, especially in patients with heart disease.
How serious is the interaction between Nortriptyline and Telavancin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Check a baseline ECG and monitor QTc and electrolytes during co-therapy. Consider an alternative antibiotic in patients with other QT risk factors.
What other medicines interact with Telavancin?
MediHelp also lists interactions of Telavancin with, for example, Thioridazine, Adagrasib, Amiodarone. The full list is on the Telavancin page.
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