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Drug interactions

Octreotide + Umeclidinium-vilanterol

Severity: Minor

Octreotide and Umeclidinium-vilanterol: minor interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Octreotide can cause bradycardia and conduction abnormalities, including QT prolongation in some patients. Vilanterol may add to arrhythmic risk, though the clinical effect is generally small.

What this interaction means in plain words

Octreotide and Umeclidinium-vilanterol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.

Octreotide belongs to Endocrine; Umeclidinium-vilanterol belongs to Respiratory.

Evidence level: Low

Why it happens

Possible additive QT effects; octreotide's effect on QT is modest.

What to do

No routine change is required. Consider an ECG in patients with other QT risk factors or established cardiac disease.

What to ask your pharmacist

  • Is there anything I should notice while taking both?
  • Do I need to tell my doctor at the next visit?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Frequently asked questions

Can I take Octreotide with Umeclidinium-vilanterol?

MediHelp rates the interaction as minor. Octreotide and Umeclidinium-vilanterol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Octreotide can cause bradycardia and conduction abnormalities, including QT prolongation in some patients. Vilanterol may add to arrhythmic risk, though the clinical effect is generally small.

How serious is the interaction between Octreotide and Umeclidinium-vilanterol?

MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine change is required. Consider an ECG in patients with other QT risk factors or established cardiac disease.

What other medicines interact with Umeclidinium-vilanterol?

MediHelp also lists interactions of Umeclidinium-vilanterol with, for example, Aclidinium, Amiodarone, Amitriptyline. The full list is on the Umeclidinium-vilanterol page.

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