Drug interactions
Ofloxacin + Telavancin
Severity: Moderate
Ofloxacin and Telavancin: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Ofloxacin can modestly prolong the QT interval and telavancin may add to it. The combination may increase arrhythmia risk in patients with other predisposing factors.
What this interaction means in plain words
Ofloxacin and Telavancin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Ofloxacin belongs to Anti Bacterial; Telavancin belongs to Anti Bacterial.
Why it happens
Additive QTc prolongation through effects on cardiac repolarization.
What to do
Check baseline ECG and electrolytes, and monitor the QTc during combined use. Consider an alternative antibacterial in patients at high arrhythmic risk.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Telavancin
- Telavancin + Thioridazine Contraindicated
- Adagrasib + Telavancin Major
- Amiodarone + Telavancin Major
- Amisulpride + Telavancin Major
- Anagrelide + Telavancin Major
- Arsenic trioxide + Telavancin Major
Other interactions of Ofloxacin
- Ofloxacin + Thioridazine Contraindicated
- Adagrasib + Ofloxacin Major
- Amiodarone + Ofloxacin Major
- Amisulpride + Ofloxacin Major
- Anagrelide + Ofloxacin Major
- Arsenic trioxide + Ofloxacin Major
Frequently asked questions
Can I take Ofloxacin with Telavancin?
MediHelp rates the interaction as moderate. Ofloxacin and Telavancin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Ofloxacin can modestly prolong the QT interval and telavancin may add to it. The combination may increase arrhythmia risk in patients with other predisposing factors.
How serious is the interaction between Ofloxacin and Telavancin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Check baseline ECG and electrolytes, and monitor the QTc during combined use. Consider an alternative antibacterial in patients at high arrhythmic risk.
What other medicines interact with Telavancin?
MediHelp also lists interactions of Telavancin with, for example, Thioridazine, Adagrasib, Amiodarone. The full list is on the Telavancin page.
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