Drug interactions
Olodaterol inhaled + Prednisone
Severity: Moderate
Olodaterol inhaled and Prednisone: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Both beta-2 agonists and corticosteroids can lower serum potassium. Together, particularly at high steroid doses, hypokalemia may occur and could provoke arrhythmias in susceptible patients.
What this interaction means in plain words
Olodaterol inhaled and Prednisone can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Additive hypokalemia from beta-2 stimulated cellular potassium uptake and mineralocorticoid-related renal potassium loss.
What to do
Check serum potassium in patients on high-dose prednisone, especially with diuretics or heart disease, and replace potassium as needed.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Prednisone
- Bcg vaccine live + Prednisone Contraindicated
- Measles vaccine + Prednisone Contraindicated
- Mifepristone + Prednisone Contraindicated
- Prednisone + Radium-223 dichloride Contraindicated
- Prednisone + Smallpox vaccine live Contraindicated
- Adenovirus types 4 and 7 live + Prednisone Major
Frequently asked questions
Can I take Olodaterol inhaled with Prednisone?
MediHelp rates the interaction as moderate. Olodaterol inhaled and Prednisone can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Both beta-2 agonists and corticosteroids can lower serum potassium. Together, particularly at high steroid doses, hypokalemia may occur and could provoke arrhythmias in susceptible patients.
How serious is the interaction between Olodaterol inhaled and Prednisone?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Check serum potassium in patients on high-dose prednisone, especially with diuretics or heart disease, and replace potassium as needed.
What other medicines interact with Prednisone?
MediHelp also lists interactions of Prednisone with, for example, Bcg vaccine live, Measles vaccine, Mifepristone. The full list is on the Prednisone page.
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