Drug interactions
Olodaterol inhaled + Quetiapine
Severity: Moderate
Olodaterol inhaled and Quetiapine: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Quetiapine can prolong the QT interval and beta2 agonists may add to cardiac effects such as tachycardia and hypokalemia. This may raise the risk of arrhythmia, although inhaled olodaterol at usual doses has low systemic exposure.
What this interaction means in plain words
Olodaterol inhaled and Quetiapine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Additive QT prolongation and beta2-mediated hypokalemia and tachycardia.
What to do
Monitor ECG and serum potassium in patients with additional QT risk factors. Use olodaterol at the labeled dose only.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Quetiapine
- Adagrasib + Quetiapine Major
- Amiodarone + Quetiapine Major
- Amisulpride + Quetiapine Major
- Amoxapine + Quetiapine Major
- Anagrelide + Quetiapine Major
- Apalutamide + Quetiapine Major
Frequently asked questions
Can I take Olodaterol inhaled with Quetiapine?
MediHelp rates the interaction as moderate. Olodaterol inhaled and Quetiapine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Quetiapine can prolong the QT interval and beta2 agonists may add to cardiac effects such as tachycardia and hypokalemia. This may raise the risk of arrhythmia, although inhaled olodaterol at usual doses has low systemic exposure.
How serious is the interaction between Olodaterol inhaled and Quetiapine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor ECG and serum potassium in patients with additional QT risk factors. Use olodaterol at the labeled dose only.
What other medicines interact with Quetiapine?
MediHelp also lists interactions of Quetiapine with, for example, Adagrasib, Amiodarone, Amisulpride. The full list is on the Quetiapine page.
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