Drug interactions
Olodaterol inhaled + Quinidine
Severity: Moderate
Olodaterol inhaled and Quinidine: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Quinidine prolongs the QT interval, and beta2 agonists can cause hypokalemia and tachycardia. Together they may increase the risk of ventricular arrhythmias, though systemic exposure to inhaled olodaterol is low.
What this interaction means in plain words
Olodaterol inhaled and Quinidine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Additive pharmacodynamic effects on cardiac repolarization and beta2-mediated hypokalemia.
What to do
Monitor ECG and serum potassium in patients with additional QT risk factors. Use the lowest effective olodaterol dose.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Quinidine
- Adagrasib + Quinidine Contraindicated
- Arsenic trioxide + Quinidine Contraindicated
- Artemether / lumefantrine + Quinidine Contraindicated
- Chloroquine + Quinidine Contraindicated
- Dofetilide + Quinidine Contraindicated
- Dronedarone + Quinidine Contraindicated
Frequently asked questions
Can I take Olodaterol inhaled with Quinidine?
MediHelp rates the interaction as moderate. Olodaterol inhaled and Quinidine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Quinidine prolongs the QT interval, and beta2 agonists can cause hypokalemia and tachycardia. Together they may increase the risk of ventricular arrhythmias, though systemic exposure to inhaled olodaterol is low.
How serious is the interaction between Olodaterol inhaled and Quinidine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor ECG and serum potassium in patients with additional QT risk factors. Use the lowest effective olodaterol dose.
What other medicines interact with Quinidine?
MediHelp also lists interactions of Quinidine with, for example, Adagrasib, Arsenic trioxide, Artemether / lumefantrine. The full list is on the Quinidine page.
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