Drug interactions
Olodaterol inhaled + Tranylcypromine
Severity: Moderate
Olodaterol inhaled and Tranylcypromine: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
MAO inhibitors may potentiate the cardiovascular effects of inhaled long-acting beta2 agonists, including tachycardia, hypertension and QT prolongation. This raises concern for arrhythmia, particularly in patients with cardiac disease.
What this interaction means in plain words
Olodaterol inhaled and Tranylcypromine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Additive adrenergic cardiovascular stimulation and possible QT effects, since MAO inhibition increases catecholamine availability.
What to do
Use olodaterol at the labeled dose only and monitor heart rate, blood pressure and ECG in patients with cardiac risk factors.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Pro+ members
Unlock the full page
Create an account and start a Pro+ trial to unlock the full management advice for Olodaterol inhaled and Tranylcypromine, the additional notes, the evidence detail and the whole-prescription interaction checker.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Try Pro+ free for 14 days on the web. No card needed.
Other interactions of Tranylcypromine
- 5-HTP + Tranylcypromine Contraindicated
- Amitriptyline + Tranylcypromine Contraindicated
- Amoxapine + Tranylcypromine Contraindicated
- Atomoxetine + Tranylcypromine Contraindicated
- Benzphetamine + Tranylcypromine Contraindicated
- Brimonidine + Tranylcypromine Contraindicated
Frequently asked questions
Can I take Olodaterol inhaled with Tranylcypromine?
MediHelp rates the interaction as moderate. Olodaterol inhaled and Tranylcypromine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. MAO inhibitors may potentiate the cardiovascular effects of inhaled long-acting beta2 agonists, including tachycardia, hypertension and QT prolongation. This raises concern for arrhythmia, particularly in patients with cardiac disease.
How serious is the interaction between Olodaterol inhaled and Tranylcypromine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Use olodaterol at the labeled dose only and monitor heart rate, blood pressure and ECG in patients with cardiac risk factors.
What other medicines interact with Tranylcypromine?
MediHelp also lists interactions of Tranylcypromine with, for example, 5-HTP, Amitriptyline, Amoxapine. The full list is on the Tranylcypromine page.
Full monographs, dosing and an interaction checker in the MediHelp app
Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.
