Drug interactions
Oxandrolone + Repaglinide
Severity: Moderate
Oxandrolone and Repaglinide: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Anabolic steroids such as oxandrolone can increase insulin sensitivity and lower blood glucose. With repaglinide this may increase hypoglycemia risk.
What this interaction means in plain words
Oxandrolone and Repaglinide can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Additive glucose lowering through enhanced insulin sensitivity and altered glucose metabolism.
What to do
Monitor blood glucose closely when oxandrolone is started, stopped or adjusted. Reduce the repaglinide dose if hypoglycemia develops.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Repaglinide
- Gemfibrozil + Repaglinide Contraindicated
- Clarithromycin + Repaglinide Major
- Clopidogrel + Repaglinide Major
- Cobicistat + Repaglinide Major
- Cyclosporine + Repaglinide Major
- Cyclosporin + Repaglinide Major
Frequently asked questions
Can I take Oxandrolone with Repaglinide?
MediHelp rates the interaction as moderate. Oxandrolone and Repaglinide can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Anabolic steroids such as oxandrolone can increase insulin sensitivity and lower blood glucose. With repaglinide this may increase hypoglycemia risk.
How serious is the interaction between Oxandrolone and Repaglinide?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood glucose closely when oxandrolone is started, stopped or adjusted. Reduce the repaglinide dose if hypoglycemia develops.
What other medicines interact with Repaglinide?
MediHelp also lists interactions of Repaglinide with, for example, Gemfibrozil, Clarithromycin, Clopidogrel. The full list is on the Repaglinide page.
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