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Drug interactions

Oxandrolone + Sitagliptin

Severity: Minor

Oxandrolone and Sitagliptin: minor interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Anabolic steroids may change insulin sensitivity and glucose levels in patients with diabetes. Combined with sitagliptin, this can modestly alter glycemic control, although the effect is inconsistent and usually small.

What this interaction means in plain words

Oxandrolone and Sitagliptin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.

Evidence level: Low

Why it happens

Anabolic-androgenic effects on insulin sensitivity and glucose metabolism; direction of effect is not well established.

What to do

Monitor blood glucose when oxandrolone is started or stopped and adjust antidiabetic therapy if needed.

What to ask your pharmacist

  • Is there anything I should notice while taking both?
  • Do I need to tell my doctor at the next visit?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Frequently asked questions

Can I take Oxandrolone with Sitagliptin?

MediHelp rates the interaction as minor. Oxandrolone and Sitagliptin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Anabolic steroids may change insulin sensitivity and glucose levels in patients with diabetes. Combined with sitagliptin, this can modestly alter glycemic control, although the effect is inconsistent and usually small.

How serious is the interaction between Oxandrolone and Sitagliptin?

MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood glucose when oxandrolone is started or stopped and adjust antidiabetic therapy if needed.

What other medicines interact with Sitagliptin?

MediHelp also lists interactions of Sitagliptin with, for example, Albiglutide, Amlodipine-benazepril, Aripiprazole. The full list is on the Sitagliptin page.

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