Drug interactions
Oxymetazoline + Terazosin
Severity: Minor
Oxymetazoline and Terazosin: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Terazosin is an alpha-1 blocker that lowers vascular tone, and oxymetazoline's alpha agonism may oppose it. Topical use leads to low systemic levels, so any change in blood pressure control is usually slight.
What this interaction means in plain words
Oxymetazoline and Terazosin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Oxymetazoline belongs to Respiratory; Terazosin belongs to Genitourinary.
Why it happens
Pharmacodynamic antagonism between an alpha-agonist and an alpha-1 blocker.
What to do
No action needed in most patients; check blood pressure if oxymetazoline is overused.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Oxymetazoline
- Isocarboxazid + Oxymetazoline Major
- Oxymetazoline + Phenelzine Major
- Oxymetazoline + Tranylcypromine Major
- Amitriptyline + Oxymetazoline Moderate
- Amoxapine + Oxymetazoline Moderate
- Clomipramine + Oxymetazoline Moderate
Other interactions of Terazosin
- Alfuzosin + Terazosin Major
- Amifostine + Terazosin Major
- Avanafil + Terazosin Major
- Doxazosin + Terazosin Major
- Dutasteride-tamsulosin + Terazosin Major
- Lofexidine + Terazosin Major
Frequently asked questions
Can I take Oxymetazoline with Terazosin?
MediHelp rates the interaction as minor. Oxymetazoline and Terazosin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Terazosin is an alpha-1 blocker that lowers vascular tone, and oxymetazoline's alpha agonism may oppose it. Topical use leads to low systemic levels, so any change in blood pressure control is usually slight.
How serious is the interaction between Oxymetazoline and Terazosin?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No action needed in most patients; check blood pressure if oxymetazoline is overused.
What other medicines interact with Oxymetazoline?
MediHelp also lists interactions of Oxymetazoline with, for example, Isocarboxazid, Phenelzine, Tranylcypromine. The full list is on the Oxymetazoline page.
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