Drug interactions
Pasireotide + Telavancin
Severity: Moderate
Pasireotide and Telavancin: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Pasireotide can prolong the QT interval and cause bradycardia, and telavancin may add to QTc lengthening. The combination can increase the risk of torsades de pointes, especially with hypokalemia or hypomagnesemia.
What this interaction means in plain words
Pasireotide and Telavancin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Pasireotide belongs to Endocrine; Telavancin belongs to Anti Bacterial.
Why it happens
Additive pharmacodynamic QT prolongation, with pasireotide-related bradycardia contributing.
What to do
Check a baseline ECG and correct potassium and magnesium before combining. Monitor the QTc and heart rate during therapy.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Telavancin
- Telavancin + Thioridazine Contraindicated
- Adagrasib + Telavancin Major
- Amiodarone + Telavancin Major
- Amisulpride + Telavancin Major
- Anagrelide + Telavancin Major
- Arsenic trioxide + Telavancin Major
Other interactions of Pasireotide
- Dronedarone + Pasireotide Contraindicated
- Pasireotide + Pimozide Contraindicated
- Amiodarone + Pasireotide Major
- Amisulpride + Pasireotide Major
- Amitriptyline + Pasireotide Major
- Anagrelide + Pasireotide Major
Frequently asked questions
Can I take Pasireotide with Telavancin?
MediHelp rates the interaction as moderate. Pasireotide and Telavancin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Pasireotide can prolong the QT interval and cause bradycardia, and telavancin may add to QTc lengthening. The combination can increase the risk of torsades de pointes, especially with hypokalemia or hypomagnesemia.
How serious is the interaction between Pasireotide and Telavancin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Check a baseline ECG and correct potassium and magnesium before combining. Monitor the QTc and heart rate during therapy.
What other medicines interact with Telavancin?
MediHelp also lists interactions of Telavancin with, for example, Thioridazine, Adagrasib, Amiodarone. The full list is on the Telavancin page.
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