Drug interactions
Prednisone + Tick-borne encephalitis vaccine
Severity: Moderate
Prednisone and Tick-borne encephalitis vaccine: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
This inactivated vaccine is safe to give, but immunosuppressive prednisone doses may reduce the antibody response. Protection against tick-borne encephalitis may be inadequate.
What this interaction means in plain words
Prednisone and Tick-borne encephalitis vaccine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Corticosteroid suppression of lymphocyte function reduces vaccine-induced antibody production.
What to do
Complete the vaccination schedule before travel or exposure, ideally before steroid therapy starts. Consider measuring antibody titres in patients on prolonged high-dose steroids.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Prednisone
- Bcg vaccine live + Prednisone Contraindicated
- Measles vaccine + Prednisone Contraindicated
- Mifepristone + Prednisone Contraindicated
- Prednisone + Radium-223 dichloride Contraindicated
- Prednisone + Smallpox vaccine live Contraindicated
- Adenovirus types 4 and 7 live + Prednisone Major
Frequently asked questions
Can I take Prednisone with Tick-borne encephalitis vaccine?
MediHelp rates the interaction as moderate. Prednisone and Tick-borne encephalitis vaccine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. This inactivated vaccine is safe to give, but immunosuppressive prednisone doses may reduce the antibody response. Protection against tick-borne encephalitis may be inadequate.
How serious is the interaction between Prednisone and Tick-borne encephalitis vaccine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Complete the vaccination schedule before travel or exposure, ideally before steroid therapy starts. Consider measuring antibody titres in patients on prolonged high-dose steroids.
What other medicines interact with Prednisone?
MediHelp also lists interactions of Prednisone with, for example, Bcg vaccine live, Measles vaccine, Mifepristone. The full list is on the Prednisone page.
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