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Drug interactions

Quercetin + Vinblastine

Severity: Minor

Quercetin and Vinblastine: minor interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Quercetin has variable effects on P-glycoprotein, and the legacy direction of reduced vinblastine exposure is uncertain. Supplement doses could alter vinblastine handling unpredictably.

What this interaction means in plain words

Quercetin and Vinblastine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.

Evidence level: Low

Why it happens

Quercetin modulates P-glycoprotein and CYP3A4, but the net effect on vinblastine is not well established.

What to do

Advise patients receiving vinblastine to avoid high-dose quercetin supplements. Monitor for altered response or toxicity.

What to ask your pharmacist

  • Is there anything I should notice while taking both?
  • Do I need to tell my doctor at the next visit?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Frequently asked questions

Can I take Quercetin with Vinblastine?

MediHelp rates the interaction as minor. Quercetin and Vinblastine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Quercetin has variable effects on P-glycoprotein, and the legacy direction of reduced vinblastine exposure is uncertain. Supplement doses could alter vinblastine handling unpredictably.

How serious is the interaction between Quercetin and Vinblastine?

MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Advise patients receiving vinblastine to avoid high-dose quercetin supplements. Monitor for altered response or toxicity.

What other medicines interact with Vinblastine?

MediHelp also lists interactions of Vinblastine with, for example, Adenovirus types 4 and 7 live, Apalutamide, Atazanavir. The full list is on the Vinblastine page.

Full monographs, dosing and an interaction checker in the MediHelp app

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