Drug interactions
quetiapine + rifampin
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Overview
↓ quetiapine → loss of efficacy.
Mechanism of action
CYP3A induction.
Clinical management
Avoid combination.
Drug reference
References
Frequently asked questions
Can I take quetiapine with rifampin?
The interaction is rated: Major. ↓ quetiapine → loss of efficacy.
How serious is the interaction between quetiapine and rifampin?
The interaction is rated: Major. Evidence level: High.
How is the interaction between quetiapine and rifampin managed?
Avoid combination.
Why do quetiapine and rifampin interact?
CYP3A induction.
Full monographs, dosing and an interaction checker in the MediHelp app
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