Drug interactions
Quetiapine + Scullcap
Severity: Minor
Quetiapine and Scullcap: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Skullcap has reputed sedative properties and may add to the sedation caused by quetiapine. Evidence is limited and the effect is probably modest.
What this interaction means in plain words
Quetiapine and Scullcap have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Possible additive CNS depression; skullcap may act on GABA receptors.
What to do
Advise patients to be cautious with driving and to report excess drowsiness. Consider stopping the herbal product if sedation is troublesome.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Quetiapine
- Adagrasib + Quetiapine Major
- Amiodarone + Quetiapine Major
- Amisulpride + Quetiapine Major
- Amoxapine + Quetiapine Major
- Anagrelide + Quetiapine Major
- Apalutamide + Quetiapine Major
Frequently asked questions
Can I take Quetiapine with Scullcap?
MediHelp rates the interaction as minor. Quetiapine and Scullcap have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Skullcap has reputed sedative properties and may add to the sedation caused by quetiapine. Evidence is limited and the effect is probably modest.
How serious is the interaction between Quetiapine and Scullcap?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Advise patients to be cautious with driving and to report excess drowsiness. Consider stopping the herbal product if sedation is troublesome.
What other medicines interact with Quetiapine?
MediHelp also lists interactions of Quetiapine with, for example, Adagrasib, Amiodarone, Amisulpride. The full list is on the Quetiapine page.
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