Drug interactions
Quinidine + Sevelamer
Severity: Minor
Quinidine and Sevelamer: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Sevelamer is a non-absorbed phosphate binder, and it could in theory bind quinidine in the gut. A real reduction in quinidine absorption has not been well documented.
What this interaction means in plain words
Quinidine and Sevelamer have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Quinidine belongs to Anti Parasitic; Sevelamer belongs to Miscellaneous.
Why it happens
Possible binding of quinidine in the gastrointestinal tract by sevelamer, which is not well established.
What to do
Give quinidine at least 1 hour before or 3 hours after sevelamer. Check quinidine levels if the response is inadequate.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Quinidine
- Adagrasib + Quinidine Contraindicated
- Arsenic trioxide + Quinidine Contraindicated
- Artemether / lumefantrine + Quinidine Contraindicated
- Chloroquine + Quinidine Contraindicated
- Dofetilide + Quinidine Contraindicated
- Dronedarone + Quinidine Contraindicated
Other interactions of Sevelamer
- Carbamazepine + Sevelamer Moderate
- Ciprofloxacin + Sevelamer Moderate
- Dichlorphenamide + Sevelamer Moderate
- Erdafitinib + Sevelamer Moderate
- Gabapentin + Sevelamer Moderate
- Mycophenolic acid + Sevelamer Moderate
Frequently asked questions
Can I take Quinidine with Sevelamer?
MediHelp rates the interaction as minor. Quinidine and Sevelamer have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Sevelamer is a non-absorbed phosphate binder, and it could in theory bind quinidine in the gut. A real reduction in quinidine absorption has not been well documented.
How serious is the interaction between Quinidine and Sevelamer?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Give quinidine at least 1 hour before or 3 hours after sevelamer. Check quinidine levels if the response is inadequate.
What other medicines interact with Quinidine?
MediHelp also lists interactions of Quinidine with, for example, Adagrasib, Arsenic trioxide, Artemether / lumefantrine. The full list is on the Quinidine page.
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