Drug interactions
Quinidine + Somatropin
Severity: Minor
Quinidine and Somatropin: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Growth hormone may increase CYP450 activity, including CYP3A4, and could lower quinidine concentrations. The evidence is limited and the effect is probably small.
What this interaction means in plain words
Quinidine and Somatropin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Quinidine belongs to Anti Parasitic; Somatropin belongs to Endocrine.
Why it happens
Somatropin may induce CYP3A4-mediated metabolism of quinidine.
What to do
Monitor the quinidine response and ECG when somatropin is started or changed. Check serum quinidine levels if efficacy appears reduced.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Quinidine
- Adagrasib + Quinidine Contraindicated
- Arsenic trioxide + Quinidine Contraindicated
- Artemether / lumefantrine + Quinidine Contraindicated
- Chloroquine + Quinidine Contraindicated
- Dofetilide + Quinidine Contraindicated
- Dronedarone + Quinidine Contraindicated
Other interactions of Somatropin
- Acarbose + Somatropin Moderate
- Albiglutide + Somatropin Moderate
- Alogliptin-metformin + Somatropin Moderate
- Alogliptin-pioglitazone + Somatropin Moderate
- Alogliptin + Somatropin Moderate
- Betamethasone + Somatropin Moderate
Frequently asked questions
Can I take Quinidine with Somatropin?
MediHelp rates the interaction as minor. Quinidine and Somatropin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Growth hormone may increase CYP450 activity, including CYP3A4, and could lower quinidine concentrations. The evidence is limited and the effect is probably small.
How serious is the interaction between Quinidine and Somatropin?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor the quinidine response and ECG when somatropin is started or changed. Check serum quinidine levels if efficacy appears reduced.
What other medicines interact with Quinidine?
MediHelp also lists interactions of Quinidine with, for example, Adagrasib, Arsenic trioxide, Artemether / lumefantrine. The full list is on the Quinidine page.
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