Drug interactions
Quinine + Triamterene
Severity: Minor
Quinine and Triamterene: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Both drugs are basic compounds that may compete for renal tubular secretion, potentially raising triamterene levels. Triamterene can also cause hyperkalemia, and quinine may affect cardiac conduction, so the combination deserves awareness.
What this interaction means in plain words
Quinine and Triamterene have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Quinine belongs to Anti Parasitic; Triamterene belongs to Cardiovascular.
Why it happens
Competition for renal tubular cationic secretion between quinine and triamterene.
What to do
Monitor serum potassium and renal function if the combination is used for more than a short course.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Quinine
- Arsenic trioxide + Quinine Contraindicated
- Dofetilide + Quinine Contraindicated
- Dronedarone + Quinine Contraindicated
- Ibutilide + Quinine Contraindicated
- Mefloquine + Quinine Contraindicated
- Nilotinib + Quinine Contraindicated
Other interactions of Triamterene
- Amiloride + Triamterene Contraindicated
- Eplerenone + Triamterene Contraindicated
- Potassium citrate / citric acid + Triamterene Contraindicated
- Potassium citrate + Triamterene Contraindicated
- Spironolactone + Triamterene Contraindicated
- Aceclofenac + Triamterene Major
Frequently asked questions
Can I take Quinine with Triamterene?
MediHelp rates the interaction as minor. Quinine and Triamterene have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Both drugs are basic compounds that may compete for renal tubular secretion, potentially raising triamterene levels. Triamterene can also cause hyperkalemia, and quinine may affect cardiac conduction, so the combination deserves awareness.
How serious is the interaction between Quinine and Triamterene?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor serum potassium and renal function if the combination is used for more than a short course.
What other medicines interact with Quinine?
MediHelp also lists interactions of Quinine with, for example, Arsenic trioxide, Dofetilide, Dronedarone. The full list is on the Quinine page.
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